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Middle East Respiratory Syndrome (MERS) - Johns Hopkins …
https://www.hopkinsmedicine.org/health/conditions-and-diseases/middle-east-respiratory-syndrome-mers
WEB410-955-5000 Maryland. 855-695-4872 Outside of Maryland. +1-410-502-7683 International. MERS is an illness that affects your respiratory system. Most cases of MERS are mild. But sometimes symptoms can be severe.
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Middle East respiratory syndrome coronavirus (MERS-CoV)
https://www.who.int/news-room/fact-sheets/detail/middle-east-respiratory-syndrome-coronavirus-(mers-cov)
WEBAug 5, 2022 · MERS-CoV is a zoonotic virus, meaning it is transmitted between animals and people. MERS-CoV has been identified and linked to human infections in dromedary camels in several Member States in the Middle East, Africa and South Asia. Human-to-human transmission is possible and has occurred predominantly among close contacts and in …
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Middle East Respiratory Syndrome (MERS) | CDC
https://www.cdc.gov/coronavirus/mers/index.html
WEBAug 2, 2019 · Middle East Respiratory Syndrome (MERS) is viral respiratory illness that is new to humans. It was first reported in Saudi Arabia in 2012 and has since spread to several other countries, including the United States. Most people infected with MERS-CoV developed severe respiratory illness, including fever, cough, and shortness of breath.
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MERS Symptoms & Complications | CDC
https://www.cdc.gov/coronavirus/mers/about/symptoms.html
WEBAug 2, 2019 · Symptoms & Complications. Most people confirmed to have MERS-CoV infection have had severe respiratory illness with symptoms of: Some people also had diarrhea and nausea/vomiting. For many people with MERS, more severe complications followed, such as pneumonia and kidney failure. About 3 or 4 out of every 10 people reported with MERS …
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MERS in the U.S. | CDC
https://www.cdc.gov/coronavirus/mers/us.html
WEBAug 2, 2019 · CDC continues to closely monitor the situation. In May 2014, CDC confirmed two unlinked imported cases of MERS in the United States—one to Indiana, the other to Florida. Both cases were among healthcare providers who lived and worked in Saudi Arabia. Both traveled to the U.S. from Saudi Arabia, where scientists believe they were infected.
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How Is MERS Different from the Flu? | Live Science
https://www.livescience.com/45578-how-is-mers-different-from-flu.html
WEBMay 13, 2014 · MERS appears to have a high death rate. So far, 145 patients out of the 538 confirmed cases have died. Influenza, has a lower death rate, but infects more people, resulting in more deaths ...
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Middle East Respiratory Syndrome: Emergence of a Pathogenic …
https://www.annualreviews.org/doi/10.1146/annurev-med-051215-031152
WEBIn 2012, a zoonotic coronavirus was identified as the causative agent of Middle East respiratory syndrome and was named MERS coronavirus (MERS-CoV). As of August 11, 2016, the virus has infected 1,791 patients, with a mortality rate of 35.6%. Although MERS-CoV generally causes subclinical or mild disease, infection can result in serious outcomes, …
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Evaluation of candidate vaccine approaches for MERS-CoV
https://pubmed.ncbi.nlm.nih.gov/26218507/
WEBJul 28, 2015 · Abstract. The emergence of Middle East respiratory syndrome coronavirus (MERS-CoV) as a cause of severe respiratory disease highlights the need for effective approaches to CoV vaccine development. Efforts focused solely on the receptor-binding domain (RBD) of the viral Spike (S) glycoprotein may not optimize neutralizing antibody …
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Ligand-induced Dimerization of Middle East Respiratory ... - PubMed
https://pubmed.ncbi.nlm.nih.gov/26055715/
WEBAug 7, 2015 · All coronaviruses, including the recently emerged Middle East respiratory syndrome coronavirus (MERS-CoV) from the β-CoV subgroup, require the proteolytic activity of the nsp5 protease (also known as 3C-like protease, 3CL(pro)) during virus replication, making it a high value target for the developm …
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Structural Definition of a Neutralization-Sensitive Epitope on the MERS …
https://pubmed.ncbi.nlm.nih.gov/31553909/
WEBSep 24, 2019 · Potently neutralizing antibodies targeting the receptor-binding domain (RBD) on MERS-CoV spike (S) protein have been characterized, but much less is known about antibodies targeting non-RBD epitopes. Here, we report the structural and functional characterization of G2, a neutralizing antibody targeting the MERS-CoV S1 N-terminal …
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