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Ticagrelor Uses, Side Effects & Warnings - Drugs.com
Jan 22, 2021 · Ticagrelor is also used to lower your risk of a first heart attack or stroke if you have decreased blood flow to the heart. Ticagrelor is also used to lower the risk of stroke and death in adults with a blockage or decreased blood flow in an artery that supplies blood to the brain. Ticagrelor is usually given together with low-dose aspirin. Carefully follow your doctor's dosing instructions.
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Ticagrelor | C23H28F2N6O4S - PubChem
Ticagrelor, a cyclopentyltriazolopyrimidine derivative, is a nonthienopyridine, P2Y12 platelet adenosine diphosphate -receptor antagonist.
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Ticagrelor - Wikipedia
The PLATO trial found that ticagrelor had better mortality rates than clopidogrel (9.8% vs. 11.7%, p<0.001) in treating patients with acute coronary syndrome. Patients given ticagrelor were less likely to die from vascular causes, heart attack, or stroke but had greater chances of non-lethal bleeding (16.1% vs. 14.6%, p=0.0084) and higher rate of major bleeding not related to coronary-artery bypass grafting (4.5% vs. 3.8%, p=0.03). While the patient group on ticagrelor had more instances of fatal intracranial bleeding, there were significantly fewer ca…
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Brilinta™ (ticagrelor) Tablets
The mean half-life is approximately 7 hours for ticagrelor and 9 hours for the active metabolite. Special Populations. The effects of age, gender, ethnicity, renal impairment, and mild hepatic impairment on the pharmacokinetics of ticagrelor are modest and do not require dose adjustment. Ticagrelor has not been evaluated in a pediatric population.
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Ticagrelor - Australian Prescriber
Oct 01, 2011 · After 12 months, the composite outcome of cardiovascular death, myocardial infarction or stroke occurred less with ticagrelor than with clopidogrel (9.8% vs 11.7%, p 1. Although ticagrelor was significantly more effective than clopidogrel in the trial, its efficacy varied between countries.
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A pilot study of the ticagrelor role in ischemic stroke ...
Patients who received ticagrelor had a better outcome regarding NIHSS improvement at 2 days and 1 week or discharge and a favorable mRS score after 1 week or discharge and at 90-day follow-up. Conclusion: Ticagrelor was noninferior to aspirin regarding safety profile. Compared with aspirin, ticagrelor had a better clinical outcome based on NIHSS and mRS in first-ever acute ischemic stroke patients who received it within 9 …
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How is ticagrelor used in the treatment of heart attack?
Ticagrelor is used for the prevention of thrombotic events (for example stroke or heart attack) in different categories of patients.
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When was ticagrelor due to be stopped soon?
Hi Andie. I had to stop Ticagrelor after 9 months (allergic reaction to Ticagrelor)and just continued with Aspirin. It is now 14 months since heart attack and stenting and am still going.! I was recommended to take for 12 months then to just continue with aspirin.
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Are there any side effects to taking ticagrelor?
Stopping ticagrelor may increase your risk of a heart attack or stroke. You should not use ticagrelor if you are allergic to it, or if you have: a history of bleeding in the brain (such as from a head injury ). asthma, COPD (chronic obstructive pulmonary disorder) or other breathing problem.
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What is the heart rate for clopidogrel and ticagrelor?
The HR actually reversed for the composite end point cardiovascular (death, MI, or stroke): 12.6% for patients given ticagrelor and 10.1% for patients given clopidogrel (HR = 1.27).
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