Keyword Analysis & Research: ochronosis
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Ochronosis - Wikipedia
https://en.wikipedia.org/wiki/Ochronosis
WebOchronosis is a syndrome caused by the accumulation of homogentisic acid in connective tissues. The condition was named after the yellowish (ocher-like) discoloration of the tissue seen on microscopic examination. Macroscopically, though, the affected tissues appear bluish-grey because of a light-scattering phenomenon known as the Tyndall effect.
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Ochronosis - StatPearls - NCBI Bookshelf
https://www.ncbi.nlm.nih.gov/books/NBK560534/
WebAug 8, 2023 · Ochronosis. Wajahat Efridi; Amit S. Dhamoon. Author Information and Affiliations. Last Update: August 8, 2023. Go to: Continuing Education Activity. Ochronosis is named for the reddish-brown hue of tissue termed "ochre-like" that was first described by a young physician named Archibald Garrod in the early-19th century.
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Alkaptonuria and ochronosis | DermNet
https://dermnetnz.org/topics/alkaptonuria-and-ochronosis
WebWhat is alkaptonuria and ochronosis? Alkaptonuria is a rare genetic disease that is characterised by passing urine that becomes black when left standing. The earliest sign of the condition is usually dark staining found in nappies or diapers of infants. The most obvious sign in adults is a thickening and blue-black discolouration of the ear ...
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Ochronosis and Alkaptonuria: Practice Essentials, …
https://emedicine.medscape.com/article/1104184-overview
WebClinical Presentation. Ochronosis is the bluish black discoloration of certain tissues, such as the ear cartilage and the ocular tissue, seen with alkaptonuria, a metabolic disorder....
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Ochronosis | Radiology Reference Article | Radiopaedia.org
https://radiopaedia.org/articles/ochronosis
WebOct 9, 2023 · The term ochronosis usually refers to the bluish-black discolouration of certain tissues, such as the ear cartilage and the ocular tissue, seen with alkaptonuria. Some authorities, however, refer to musculoskeletal manifestations of alkaptonuria as …
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Ochronosis - Genetic and Rare Diseases Information Center
https://rarediseases.info.nih.gov/diseases/7231/ochronosis/
WebSummary. Ochronosis is the bluish-black or grey-blue discoloration of the skin, especially the ear cartilage, the ocular (eye) tissue, and other body locations. It can occurs in individuals with alkaptonuria, an inherited metabolic disorder; or because of exposure to various substances.
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Ochronosis - Rheumatology Advisor
https://www.rheumatologyadvisor.com/ddi/ochronosis/
WebNov 15, 2022 · Derived from the Greek word “ochre,” meaning pale yellow, ochronosis is a rare disease characterized by a blue-black or gray-blue pigmentation. It is caused by deposits of yellow or ochre-colored pigment and typically affects the skin, the cartilage of the ears, and eye sclerae.
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Ochronosis - Basic Science - Orthobullets
https://www.orthobullets.com/basic-science/9046/ochronosis
WebDec 26, 2023 · Ochronosis is a metabolic arthropathy caused by alkaptonuria with excess homogentistic acid deposited in the joints. Patients present with early degenerative joint disease, spondylitis, and black urine. Diagnosis is made with detection of …
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Ochronosis - an overview | ScienceDirect Topics
https://www.sciencedirect.com/topics/medicine-and-dentistry/ochronosis
WebOchronosis (alkaptonuria) is an autosomal recessive defect in homogentisic acid oxidase resulting in the accumulation of homogentisic acid in tissues, and pigmentation of cartilage (e.g., ears, sclerae, heart valves), calcification and ossification of the intervertebral disks, accelerated osteoporosis and osteoarthritis, and vascular disease.
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What Is Ochronosis (Alkaptonuria)? - All About Vision
https://www.allaboutvision.com/conditions/related/alkaptonuria-and-ochronosis/
WebDec 19, 2022 · Ochronosis can be found in: Tendons. Ligaments Sclera (the white part of the eye) Heart valves. Blood vessel lining. Skin. The average age of onset for ochronosis-related eye symptoms is around 30. This is because homogentisic acid takes time to build up in tissues before hyperpigmentation occurs.
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