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The Pathogenesis of Hashimoto's Thyroiditis: Further ...
Hashimoto's thyroiditis (HT) is part of a spectrum of thyroid autoimmune conditions and this review provides an update on the latest developments in the field. HT has a genetic predisposition with a number of immune-related and thyroid-specific genes conferring disease susceptibility. However, disentangling genes with protective and predisposing effect is a complex process that requires further work.
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Hashimoto's Disease | NIDDK
In people with Hashimoto’s disease. the immune system makes antibodies that attack the thyroid gland. large numbers of white blood cells, which are part of the immune system, build up in the thyroid. the thyroid becomes damaged and can’t make enough thyroid hormones.
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Hashimoto's thyroiditis: An update on pathogenic ...
Although the exact etiology has not been fully elucidated, Hashimoto's thyroiditis is related to an interaction among genetic elements, environmental factors and epigenetic influences. Cellular and humoral immunity play a key role in the development of the disease; thus, a T and B cells inflammatory infiltration is frequently found.
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Hashimoto's thyroiditis - Wikipedia
The strong genetic component is borne out in studies on monozygotic twins, with a concordance of 38–55%, with an even higher concordance of circulating thyroid antibodies not in relation to clinical presentation (up to 80% in monozygotic twins). Neither result was seen to a similar degree in dizygotic twins, offering strong favour for high genetic aetiology. Certain medications or drugs have been associated with altering and interfering with thyroid function. O…
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What causes Hashimoto's disease?
Hashimoto's disease also known as Hashimoto's thyroiditis is an autoimmune disease caused due to the defected immune system.
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How do you get Hashimoto's disease?
Hashimoto’s occurs when your genes are predisposed to an autoimmune condition; when there’s a trigger (like a toxin or chemical exposure, nutrient deficiency, a sensitivity to gluten, dairy, or soy, infections, etc.); and when you have a leaky gut (intestinal permeability).
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