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Department of Immunology | Immunology
https://immunology.hms.harvard.edu/
Aug 19, 2021 . Interferon-α-producing plasmacytoid dendritic cells drive the loss of adipose tissue regulatory T cells during obesity. Cell Metabolism 2021 Jul 8;S1550-4131(21)00277-1. doi: 10.1016/j.cmet.2021.06.007.
DA: 79 PA: 49 MOZ Rank: 39
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Self-reactivity controls functional diversity of naive CD8
https://www.nature.com/articles/s41467-021-26351-3
Oct 18, 2021 . a Ly6C, CD183, and CD103 expression on B6 CD44 lo and CD44 hi CD8 + T cells. b Percentage of Ly6C +, CD183 +, and CD103 − cells in CD5 lo and CD5 hi B6 naive CD8 + …
DA: 99 PA: 80 MOZ Rank: 56
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Microbiota triggers STING-type I IFN-dependent monocyte
https://www.cell.com/cell/fulltext/S0092-8674(21)01066-7
Oct 07, 2021 . The gut microbiota tunes the pro/anti-tumorigenic balance of the tumor microenvironment via a STING-type I IFN-dependent mechanism. Feeding a high-fiber diet or transferring the fecal microbiota from immune checkpoint blockade (ICB) responder melanoma individuals triggers this pathway and programs intratumoral mononuclear phagocytes to promote anticancer immunity and …
DA: 7 PA: 20 MOZ Rank: 78
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CD73-mediated adenosine production by CD8 T cell-derived
https://www.nature.com/articles/s41467-021-26134-w
Oct 08, 2021 . Even though this pathway is widely accepted to be valid also in the human system, gene expression data from the Human Protein Atlas 26,27 and the …
DA: 86 PA: 89 MOZ Rank: 84
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Confronting false discoveries in single-cell differential
https://www.nature.com/articles/s41467-021-25960-2
Sep 28, 2021 . Der et al., 2019 84. scRNA-seq data of skin samples from patients with lupus nephritis (LN) and healthy controls was obtained from ImmGen …
DA: 39 PA: 3 MOZ Rank: 63
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Investigating the shared genetic architecture between
https://www.nature.com/articles/s41467-021-25768-0
Sep 24, 2021 . An epidemiological association between multiple sclerosis (MS) and inflammatory bowel disease (IBD) is well established, but whether this reflects a shared genetic aetiology, and whether ...
DA: 56 PA: 70 MOZ Rank: 93
