Cystic fibrosis
https://www.patientslikeme.com/conditions/cystic-fibrosis
Also known as: CFContent medically reviewed byDr. Karthikeya T MMD, Internal MedicineView full profile onLinkedInWhat is Cystic fibrosis?Treatment optionsNutritional adviceHow is this diagnosed?Symptoms & ReportsSymptoms & ReportsIf you or someone you know is exhibiting symptoms of Cystic fibrosis, seek medical attention immediately.CF affects cells that make mucus, sweat and digestive fluids. These fluids are thick in CF patients and cause the blockage of ducts throughout the body leading to a range of symptoms. The lungs and digestive system are the main areas that are affected. Symptoms may appear soon after birth or in early childhood. In rare cases, they are not manifested until adulthood.Persistent cough with phlegmPostnasal dripSalty tasting skinWheezingShortness of breathSinusitisInability to exerciseMale infertilityRepeated lung infectionsFoul-smelling, bulky greasy stoolsPoor growth and low body weight despite a good appetiteBlockage in the intestinal especially in newbornsDiarrhea/constipation Persistent cough with phlegm Postnasal drip Salty tasting skin Wheezing Shortness of breath Sinusitis Inability to exercise Male infertility Repeated lung infections Foul-smelling, bulky greasy stools Poor growth and low body weight despite a good appetite Blockage in the intestinal especially in newborns Diarrhea/constipation Cystic fibrosis is a genetic disorder caused by mutation (change) in the cystic fibrosis transmembrane conductance (CFTR) gene. CFTR controls the flow of salt and fluids in and out of cells and defect in this gene causes a build-up of thick, sticky mucus in the body’s ducts. CF is seen only when both copies of the gene (one inherited from each parent) are defective. The risk factors include: Family history Damaged airways (bronchiectasis) Chronic infections: Mucus encourages the growth of microbes Growths in the nose (nasal polyps) Coughing up blood (hemoptysis). Over time, cystic fibrosis can cause thinning of the airway walls Pneumothorax: Can cause chest pain and breathlessness. Respiratory failure Acute exacerbations Nutritional deficiencies Diabetes Blocked bile duct Intestinal obstruction Distal intestinal obstruction syndrome (DIOS)
Persistent cough with phlegm
Postnasal drip
Salty tasting skin
Wheezing
Shortness of breath
Sinusitis
Inability to exercise
Male infertility
Repeated lung infections
Foul-smelling, bulky greasy stools
Poor growth and low body weight despite a good appetite
Blockage in the intestinal especially in newborns
Diarrhea/constipation
Cystic fibrosis is a genetic disorder caused by mutation (change) in the cystic fibrosis transmembrane conductance (CFTR) gene.
CFTR controls the flow of salt and fluids in and out of cells and defect in this gene causes a build-up of thick, sticky mucus in the body’s ducts.
CF is seen only when both copies of the gene (one inherited from each parent) are defective.
The risk factors include:
Family history
Damaged airways (bronchiectasis)
Chronic infections: Mucus encourages the growth of microbes
Growths in the nose (nasal polyps)
Coughing up blood (hemoptysis). Over time, cystic fibrosis can cause thinning of the airway walls
Pneumothorax: Can cause chest pain and breathlessness.
Respiratory failure
Acute exacerbations
Nutritional deficiencies
Diabetes
Blocked bile duct
Intestinal obstruction
Distal intestinal obstruction syndrome (DIOS)
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