Keyword Analysis & Research: apixaban reversal
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Anticoagulation Reversal Guideline for Adults - American …
https://www.heart.org/-/media/files/professional/quality-improvement/hemorrhagic--stroke/hemorrhagic-stroke-toolkit-page/5_18_2021/anticoagulation-reversal-guideline-for-adults-5182021.pdf?la=en
Web Resultanticoagulant reversal outweighs the risk of thrombosis (either from the reversal agent itself or normalization of coagulation in a patient with underlying thromboembolic risk). These recommendations are meant to serve as general guidelines and should not replace clinical judgment.
DA: 42 PA: 8 MOZ Rank: 91
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ANTICOAGULANTS: THE GUIDE TO REVERSAL - OHSU
https://www.ohsu.edu/sites/default/files/2019-08/Reversing%20Antithrombotic%20Therapy.pdf
Web ResultReverse if patient shows signs of intracranial hemorrhage. 1. Idarucizumab 5 grams (two 2.5g vials) Xa Inhibitors . Apixaban (Eliquis) ®. Reverse if patient shows signs of life threatening bleeding . Kcentra (4 factor PCC) 50 units/kg. Andexanet (dosing below) Edoxaban (Savaysa®)
DA: 53 PA: 28 MOZ Rank: 45
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Anticoagulant reversal - EMCrit Project
https://emcrit.org/ibcc/reverse/
Web ResultSep 25, 2021 · Non-urgent supratherapeutic INR. Approach to DOAC reversal. Dabigatran. Factor Xa inhibitors (riveroXABAN, apiXABAN, edoXABAN, fondaparinux) Reversal of other agents. Thrombolytics (e.g. tPA) Heparin reversal. Antiplatelet agent reversal. Pharmacology of broad-spectrum reversal agents. …
DA: 35 PA: 8 MOZ Rank: 35
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Management of bleeding in patients receiving direct oral ... - UpToDate
https://www.uptodate.com/contents/management-of-bleeding-in-patients-receiving-direct-oral-anticoagulants
Web ResultFeb 16, 2024 · Anticoagulant reversal - General strategy for anticoagulant reversal - Dabigatran reversal - Factor Xa inhibitors. Overview of factor Xa inhibitor reversal; Andexanet alfa; Clotting factor products - PCCs and aPCCs - Recombinant activated factor VII (rFVIIa) - Plasma products; Antifibrinolytics and other pro-hemostatic …
DA: 20 PA: 31 MOZ Rank: 6
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Emergency Reversal of Anticoagulation - PMC - National Center …
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6754204/
Web ResultAug 6, 2019 · Apixaban (Eliquis), rivaroxaban (Xarelto), edoxaban (Savaysa), and betrixaban (Bevyxxa) reversibly and competitively inhibit free and clot-bound factor Xa. With the exception of betrixaban, which has a more limited scope of indications, Xa agents are FDA-approved for stroke and systemic embolism prevention in …
DA: 58 PA: 6 MOZ Rank: 37
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Reversal of direct oral anticoagulants: Highlights from the
https://www.ccjm.org/content/88/2/98
Web ResultThe 2019 guideline from the Anticoagulation Forum provides clear instructions on how to use 2 agents for reversing the effects of direct oral anticoagulants (DOACs): idarucizumab for dabigatran-associated bleeding and andexanet alfa for bleeding associated with rivaroxaban and apixaban.
DA: 21 PA: 40 MOZ Rank: 14
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Practical Guide for Anticoagulant and Antiplatelet Reversal in …
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9963371/
Web ResultFeb 11, 2023 · Andexanet alfa and idarucizumab are specific reversal agents for DOACs and DTIs, respectively. Protamine sulfate is the solely approved reversal agent for unfractionated heparin (UFH) and low-molecular-weight heparin (LMWH). However, there are no specific reversal agents for antiplatelets.
DA: 79 PA: 84 MOZ Rank: 1
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Andexanet Alfa for Anticoagulant Reversal - American College of …
https://www.acc.org/latest-in-cardiology/ten-points-to-remember/2021/03/26/18/33/andexanet-alfa-for-anticoagulant-reversal
Web ResultMar 26, 2021 · Andexanet alfa is approved for patients taking apixaban or rivaroxaban who require reversal of anticoagulation due to life-threatening or uncontrolled bleeding.
DA: 22 PA: 42 MOZ Rank: 43
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ACC Consensus on Management of Anticoagulant-Related Bleeding
https://www.acc.org/latest-in-cardiology/ten-points-to-remember/2020/07/10/11/26/2020-acc-expert-consensus-decision-pathway-on-bleeding
Web ResultJul 14, 2020 · Use of an anticoagulant “reversal” or hemostatic agent should be considered for life-threatening bleeding or major bleeding that does not resolve with initial management. Reversal agents should not be used for most patients with a nonmajor bleeding event.
DA: 76 PA: 85 MOZ Rank: 36
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Specific Antidotes for Direct Oral Anticoagulant Reversal
https://www.ahajournals.org/doi/10.1161/CIRCULATIONAHA.119.041687
Web ResultOct 28, 2019 · The Food and Drug Administration granted accelerated approval for patients treated with apixaban or rivaroxaban, when reversal is needed because of life-threatening or uncontrolled bleeding, beginning in May 2018 after the intermediate analysis of the ANNEXA-4 study (The Andexanet Alfa, a Novel Antidote to the …
DA: 92 PA: 26 MOZ Rank: 1