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Centromere - Definition, Function and Types | Biology Dictionary
https://biologydictionary.net/centromere/
WEBApr 28, 2017 · Centromere Definition. The centromere is the point on a chromosome where mitotic spindle fibers attach to pull sister chromatids apart during cell division. When a cell seeks to reproduce itself, it must first make a complete copy of each of its chromosomes, to ensure that their daughter cell receives a full complement of the parent …
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Centromere - Wikipedia
https://en.wikipedia.org/wiki/Centromere
WEBThe physical role of the centromere is to act as the site of assembly of the kinetochores – a highly complex multiprotein structure that is responsible for the actual events of chromosome segregation – i.e. binding microtubules and signaling to the cell cycle machinery when all chromosomes have adopted correct attachments to the spindle, so …
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Centromere | chromosome, DNA, replication | Britannica
https://www.britannica.com/science/centromere
WEBcentromere, structure in a chromosome that holds together the two chromatids (the daughter strands of a replicated chromosome). The centromere is the point of attachment of the kinetochore, a structure to which the microtubules of the …
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Centromere - National Human Genome Research Institute
https://www.genome.gov/genetics-glossary/Centromere
WEB4 days ago · Centromere. updated: April 15, 2024. Definition. 00:00. … The centromere appears as a constricted region of a chromosome and plays a key role in helping the cell divide up its DNA during division (mitosis and meiosis). Specifically, it is the region where the cell’s spindle fibers attach.
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Centromere Structure and Function - PMC - National Center for
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6535225/
WEBAbstract. The centromere is the genetic locus that specifies the site of kinetochore assembly, where the chromosome will attach to the kinetochore microtubule. The pericentromere is the physical region responsible for the geometry of bi-oriented sister kinetochores in metaphase.
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The variation and evolution of complete human centromeres
https://www.nature.com/articles/s41586-024-07278-3
WEBApr 3, 2024 · Metrics. Human centromeres have been traditionally very difficult to sequence and assemble owing to their repetitive nature and large size 1. As a result, patterns of human centromeric...
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Centromeres: From chromosome biology to biotechnology …
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9616519/
WEBJul 7, 2022 · Centromeres are the specialized chromosomal regions that are required for the maintenance of genomic stability during cell divisions, and their inheritance and function are strictly dependent on genetic and epigenetic components in most species.
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Centromeres: unique chromatin structures that drive chromosome
https://www.nature.com/articles/nrm3107
WEBApr 21, 2011 · Centromeres: unique chromatin structures that drive chromosome segregation. Jolien S. Verdaasdonk & Kerry Bloom. Nature Reviews Molecular Cell Biology 12 , 320–332 ( 2011) Cite this...
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The molecular basis for centromere identity and function
https://www.nature.com/articles/nrm.2015.5
WEBNov 25, 2015 · Abstract. The centromere is the region of the chromosome that directs its segregation in mitosis and meiosis. Although the functional importance of the centromere has been appreciated for more...
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Centromeres - Structure, Functions and Types of Centromeres
https://byjus.com/biology/centromere/
WEBCentromeres can be defined as the compressed region or a part of elongated chromosomes. It is the specialized DNA sequence in the chromosomes that links or holds together the pair of sister chromatids. The centromeres are also involved in separating the chromosome into a short arm (p) and a long arm (q).
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